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A mouse model with exons 3 and 4 deletions of the Mecp2 gene ( Mecp2B ) appears to have elongated mitochondria in the hippocampal axons and dendrites [365], and increased oxidative stress seen by increased fluorescence of the redox probe roGFP1 both in the mitochondria and cytosol [366]

K., Nikulin, M

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Unfortunately, the current clinical evidence is limited, because it is generally based upon animal studies, case reports and low-quality observational data, which are prone to confounding and biases (see also the review by St-Onge et al