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Sequential treatment is simpler and may avoid supplement interactions

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Because the digestive system is bypassed entirely, 100% of the administered dose enters circulation immediately

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Cagrilintides longer measured half-life (roughly 78 days versus about 5 days for tirzepatide) is a pharmacokinetic fact from its own study not evidence of a better outcome

Alcohol consumption can affect glycemic control, and the combination of GLP-1 therapy with alcohol might increase hypoglycemia risk, particularly in patients taking concomitant insulin or sulfonylureas