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Conversely, dosing intermittence shifts the glucocorticoid metabolic program from pro-wasting, i.e., atrophy and decreased bioenergetics with once-daily prednisone, to pro-ergogenic, i.e., increased bioenergetics and muscle mass with once-weekly prednisone in young adult mice, counteracting the muscle detriments induced by diet-induced obesity (23)

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This is why many health-conscious adults look for ways to support their internal levels through nutrition and targeted supplementation

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Dejgaard TF, Schmidt S, Frandsen CS et al (2020) Liraglutide reduces hyperglycaemia and body weight in overweight, dysregulated insulin-pump-treated patients with type 1 diabetes: the Lira Pump triala randomized, double-blinded, placebo-controlled trial

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