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All doses of obesity drug retatrutide resulted in clinically meaningful weight loss, while people with severe obesity on the highest dose lost up to 30% of their body weight over two years, topline results of a phase III clinical trial have shown

A study in July 2024 by researchers at Mass Eye and Ear in Boston found that people taking semaglutide for type 2 diabetes or weight loss had a higher risk of developing nonarteritic anterior ischemic optic neuropathy, an eye condition that can cause blindness, than people taking medications other than GLP-1 drugs for diabetes or obesity

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The drug had to be injected twice a day, which had to be done within 15-30 minutes before breakfast and dinner

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Mounjaro FDA-approved for type 2 diabetes treatment