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When activated, these receptors trigger several beneficial effects: Enhanced insulin secretion in response to elevated blood glucose levels Suppression of glucagon release , reducing hepatic glucose production Delayed gastric emptying , which promotes satiety and reduces appetite Direct effects on appetite centres in the hypothalamus, leading to reduced food intake Commonly prescribed GLP-1 receptor agonists available in the UK include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide (Byetta, Bydureon)
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They found that the use of semaglutide was associated with a much greater risk of optic nerve problems than occurred in people taking other drugs
Fux M, Benjamin J, Belmaker RH
When To Call Your Clinician Even with the best plan, you might face challenges after stopping weight loss medications