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28,29 Meanwhile, mutants H268A, W340A and R344A decreased GLP-2 potency by 457-, 34- and 16-fold, respectively (Fig

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A value of P 0.05, GSHee versus vehicle)

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doi: 10.1080/19490976.2022.2108655, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 85

Tirzepatide (GLP-1/GIP) Tirzepatide is a first-in-class dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptor agonist, providing synergistic metabolic effects for diabetes and obesity research