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By the Numbers (Clinical Trial Averages): Tirzepatide Wins for: Greater Average Weight Loss: 22.5% vs 14.9% More Patients Reaching 20% Loss: 63% vs not reported Higher Percentage Reaching 15% Loss: 78% vs 50.5% Continued Weight Loss: Patients continued losing weight throughout 72 weeks Semaglutide Still Highly Effective: 86% of patients lost at least 5% of body weight 69% of patients lost at least 10% of body weight Longer market history with real-world data Proven cardiovascular benefits in studies Factors Beyond Weight Loss Numbers: Side Effect Tolerance: If you experience severe nausea with one medication, the one you can actually take consistently is the more effective choice for you

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The retatrutide stays at 4 mg while cagrilintide increases

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As the newest addition to incretin-based drugs, tirzepatide harbors the potential to counteract most of the pathogenetic mechanisms underpinning CKD in T2D displaying unprecedented features in terms of glucose and weight lowering, accompanied by promotion of insulin sensitivity, control of SBP, dyslipidemia, and biomarkers of inflammation and endothelial dysfunction

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