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Psychiatry 22 , 689702 (2017)

Due to its effects on blood pressuretypically a transient increase of 6 mmHg in systolic blood pressure and 3 mmHg in diastolic blood pressurebremelanotide is considered contraindicated for individuals with uncontrolled hypertension or cardiovascular disease

The regulator also raised concerns related to the use of insulin icodec in type 1 diabetes (T1D)

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