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[DOI] [PMC free article] [PubMed] [Google Scholar] Sechi G, Deledda MG, Bua G, Satta WM, Deiana GA, Pes GM, Rosati G

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134 The NLRP3 is also upregulated resulting from activated NF-B, and activates caspase 1 which induces cell pyroptosis, a type of programmed cell death characterized by the formation of pores in the plasma membrane, leading to the release of proinflammatory cytokines and subsequent cell lysis 38,135 (Fig