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Conversely, it remains possible that some antibody paratopes could neutralize the virus by interfering with the structural transition of gB and/or interaction with its neighbouring molecules due to the steric hindrance, which is much greater than that imposed by a nanobody

10.1002/jcla.23648 J

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Increasingly, human trials demonstrate distinct responder and non-responder subgroups, even when participants receive the same strain and dosage, with differences correlated to baseline microbial community structures, metabolic profiles, and gut transit characteristics (573)

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