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Neuropeptides 36 , 7784 (2002)
16 The agencies pointed out 17 that commenters also noted that enabling States to more easily and, perhaps, therefore, more frequently, update their EHB-benchmark plans could result in expanded coverage for, among other things, maternity care, substance use disorder care, obesity care, and chronic disease management. So while most current EHB benchmark plans do not include coverage for anti-obesity medications, that could certainly change in the coming years
But the Phase 2 curve suggests total weight loss could reach 20 to 25% of body weight at peak effect for the highest dose group
Older patients (especially those over 60) and those with preexisting cardiovascular disease benefit from lower GLP-1 starting doses, slower titration, and more frequent monitoring