SEP-479 oral small-molecule agonist of the parathyroid hormone 1 receptor (PTH1R) aimed at treating hypoparathyroidism Recent Highlights: In May 2025, Septerna signed an exclusive global collaboration with Novo Nordisk worth up to $2.2B to co-develop oral small molecule GLP-1, GIP, and glucagon receptor agonists
Eur J Pharmacol (2008) 587(1-3):1127
This unpleasant symptom occurs when certain foods are broken down by bacteria in the digestive tract
For research teams comparing next-generation incretin systems, Retatrutide provides a high-interest model for studying how multiple peptide receptor pathways may interact in broader metabolic signaling environments
The third approach aims to enhance endogenous GLP-1 production from intestinal L-cells
After six months, theyll be checked for improvements in metrics such as pain level, mood, sleep patterns, cholesterol, and blood sugar