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Keywords: adipocyte, lipolysis, triacylglyceride lipase, perilipin, desnutrin/ATGL, hormone-sensitive lipase INTRODUCTION White adipose tissue (WAT) triacylglycerol (TAG) is the major energy reserve in higher eukaryotes

The methodological robustness of the study, and consistency with recent literature support that use of GLP-1 RA does not appear to be associated with an increased risk of suicide or suicide attempts

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For weight management specifically, long-term data is newer but increasingly positive

Evaluate whether tirzepatide side effects are contributing to dehydration

The glucose-dependent nature of this effect reduces the risk of hypoglycemia