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Standard cycle is 8 weeks on, 8 weeks off

"Patients will suffer from the usual side-effects of extreme tiredness, irrational behaviour, mood swings, memory problems." The British National Formulary, which sets guidelines for the use of vitamin B12 in pernicious anaemia, said the practice was based on the best available evidence base

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Some studies show a small increase in resting metabolic rate, possibly mediated by improved insulin sensitivity and reduced lipotoxicity in tissues

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