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RYBELSUS : Offered as oral tablets, RYBELSUS is used for daily administration

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Fedeli V, Unfer V, Dinicola S, Lagan AS, Canipari R, Monti N, et al

Prescription GLP-1 receptor agonists are FDA-approved drugs with extensive clinical trial data that directly activate GLP-1 receptors

Increasing evidence has demonstrated that GLP-1 analogues can cross the blood-brain barrier, protect dopaminergic neurons in the substantia nigra, and rescue motor activity and cognitive functions in PD animal models (5961)