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I'm a gut health dietician at Oswald Digestive Clinic, where we help individuals improve and resolve their bothersome gut issues

Starting at a higher dose would likely result in more side effects

Glucagon-like peptide-1 agonists, or GLP-1s, developed for diabetes patients By John Lovett Apr

Studies have found that people taking GLP-1s for obesity feel significantly less hungry and eat fewer calories typically around 16-39% less (4)

Some researchers transition from retatrutide to a lower-cost compound for maintenance purposes

The decision is primarily driven by rising costs, with BCBS MA reporting a $400 million operating loss in 2024, partly due to spending on GLP-1 drugs