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Since reductions in tumour size could be due to a decrease in cancer cell number and/or fibrosis in tumours, these parameters were assessed histologically

305,306 Despite the biodegradability and biocompatibility of PLL, its in vivo activity remains limited due to its high toxicity, low transfection efficiency, and poor endosomal escape ability

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For Systemic Application (via Subcutaneous Injection): A standard protocol for general systemic research often starts at the lower end of this spectrum