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Within approved clinical trial settings, the preparation of injectable investigational medicinal products (IMPs) must comply with Good Clinical Practice (GCP), the trial protocol, and local aseptic compounding policies

In a clinical trial, the highest dose of orforglipron led to 11.2 percent weight loss at 72 weeks

The FDA has issued warnings for semaglutide, that some compounded semaglutide may contain salt forms of semaglutide, like semaglutide sodium or semaglutide acetate, instead of the base form found in FDA-approved drugs like Ozempic

Final takeaway GLP-1 medications and breastfeeding are not a simple yes-or-no internet question

Risks of compounded tirzepatide include dosing errors, contamination or impurities, and unapproved ingredients or formulations

Thompson, C