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Article | July 24, 2025 Trimming time: metabolomics insights to speed development of GLP-1 therapies Multiple GLP-1-based therapies for type 2 diabetes and obesity have been approved in recent years, reflecting their strong clinical effectiveness in improving glycemic control

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[5] Patients should be advised to maintain hydration and inform their provider if severe vomiting or diarrhea occurs, as that could affect drug absorption or lead to dehydration

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The INR - or other appropriate coagulation tests - should be checked weekly until the values stabilize and then monthly, in patients taking anticoagulants together with the drug