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On the one hand, it boosts immunity against foreign invasion while on the other hand it modulates tissue responses, downregulating proinflammatory and up-regulating anti-inflammatory cytokines

A novel HGF/SF Receptor (MET) agonist transiently delays the disease progression in an amyotrophic lateral sclerosis mouse model by promoting neuronal survival and dampening the immune Dysregulation

A pretty horrific experience for anyone to go though and all completely avoidable when done with medics who can prevent and treat complications

What community sources describe, explicitly as anecdote rather than guidance: Reports of pausing when headache, irritability, or GI symptoms persist or intensify

Sharper by week two

But again, in the absence of clinical trials, we still don't know if and how they are working in humans