Among participants on the 12mg dose, 91.7% achieved at least 10% body weight reduction by week 48
Pharmacological considerations: Retatrutide slows gastric emptying, which may alter the absorption of some oral medicines including oral contraceptives
Retatrutide tends to show steeper initial weight loss curves given its broader metabolic effects, while cagrilintide shows a more gradual, steady decline
residents occurred in April 2023
Incretin-like drugs mimic these hormones, and while we do not have any head-to-head trials, you can see from the informative Figure below, summarizing best results of this family of drugs to date, moving from single agonist GLP-1 to double and then triple (GLP-1-GIP-GCG), there is incremental body weight loss
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