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Dermatologists prescribe a low dose oral tranexamic acid for melasma treatment because it poses a very low risk for deep vein thrombosis, thromboembolism, and possible stroke, while still being effective in treating melasma

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separate if possible Proton pump inhibitors : Long-term use may reduce magnesium absorption (MHRA Drug Safety Update), potentially increasing supplementation needs Diuretics : Particularly loop and thiazide diuretics can increase urinary magnesium losses Always consult the British National Formulary (BNF) or individual medication SmPCs for specific separation timing recommendations

In cases of initial disagreement, the two pathologists first re-examined the corresponding slides together to reach a consensus

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