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Post-cycle therapy after short-term anabolic-androgenic steroid use: comparative outcomes in recreational bodybuilders

A retrospective cohort design was used, comparing patients with a semaglutide/tirzepatide-type weight loss medication prescription to those without, in separate opioid and alcohol use disorder cohorts

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It is also a substrate for enzymes like sirtuins and poly(ADP-ribose) polymerases (PARPs), which regulate gene expression, DNA repair, and cellular stress responses

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These medications improve blood sugar control and reduce appetite, making them effective tools in managing diabetes and obesity