Among people with no prior history of addiction, those taking GLP-1 drugs were less likely to develop substance-use disorders across every substance studied
Cephalalgia 42 , 815826 (2022)
Kopec AK, Abrahams SR, Thornton S, Palumbo JS, Mullins ES, Divanovic S, Weiler H, Owens AP 3rd, Mackman N, Goss A, van Ryn J, Luyendyk JP, Flick MJ (2017) Thrombin promotes diet-induced obesity through fibrin-driven inflammation
The honest summary is therefore: mechanistically rich, preclinically supported (but not uniformly) for tissue repair in animals, and clinically unproven in humans
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