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Macrophages of the vascular wall can collect iron, and iron overload in turn causes macrophages to transition to an anti-inflammatory phenotype, which leads to inflammation, oxidative stress, and increased plaque formation

They are not approved by the FDA for human therapeutic use

Simultaneously, IL-6 and IFN- further reinforce the pro-inflammatory state of microglia via the JAK/STAT axis, enabling the sustained expression of inflammatory cytokines even in the absence of persistent exogenous stimuli (175, 177)

quilibre inflammatoire : En rgulant ltat redox des cellules, il contribue maintenir une rponse inflammatoire quilibre, ce qui constitue un argument de vente cl pour les formulations modernes de soutien immunitaire

Korenevsky AV, Milyutina YP, Bukalyov AV, Baranova YP, Vinogradova IA, Arutjunyan AV