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GHK-Cu exerts antioxidant and cytoprotective effects primarily through broad modulation of gene expression

It interacts weakly with receptors such as ER/ER, but its principal actions arise from regulating intracellular signaling networks including NF-B, Nrf2, PI3K/AKT, PTEN, and TGF-/Smad

Obesity: Excess body fat accumulation negatively impacting health

This work suggests that combinatorial pharmaceutical targeting of GLP-1R and GIPR will increase efficacy in treating obesity and diabetes by reducing nausea and vomiting

Determination of serum parameters Serum levels of triglycerides (TG), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), Creatine kinas-MB (CK, CK-MB), Lactate dehydrogenase (LDH) and fasting blood glucose (FBG) were analyzed using a spectrophotometrically biochemistry analyzer