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[2] During a monotherapy clinical trial of topiramate in the treatment of epilepsy in adults, hypertonia was reported in 0% of patients receiving 50 mg/day and 3% of patients receiving 400 mg/day

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Thiamin (B1): Replenishes energy lost during alcohol metabolism Pantothenic Acid (B5): Supports adrenal health to combat fatigue

The reagents for introducing these N-protective groups are the acyl chlorides or anhydrides shown in the left portion of the above diagram

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