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Summary GLP-1RAs confer favourable body composition outcomes, with clinical implications for obesity, sarcopenic obesity, and broader metabolic disease management

Common Off-Label Uses Polycystic Ovary Syndrome (PCOS) Some providers prescribe GLP-1s to improve insulin resistance, weight-related symptoms, and menstrual regularity Small studies show potential benefits Infertility / Preconception Support Off-label use in people trying to conceive (especially those with an elevated BMI and/or insulin resistance)

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However, none of those bills are expected to gain traction this year

J.PurohitV.et al (2020)