A GLP-1 receptor agonist works by mimicking a hormone your body naturally produces after you eat
This and other trials have shown improvements in patients lipid profiles with the most pronounced impact on reduction of triglycerides
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Table 3 Results of a 52-week Monotherapy Trial in Adults with Type 2 Diabetes Mellitus a Figure 3 Mean HbA 1c for Adult Patients with Type 2 Diabetes Mellitus who Completed the 52-week Trial and for the Last Observation Carried Forward (LOCF, intent-to-treat) data at Week 52 (Monotherapy) Combination Therapy Add-on to Metformin In this 26-week trial, 1,091 adult patients with type 2 diabetes mellitus were randomized to liraglutide injection 0.6 mg, liraglutide injection 1.2 mg, liraglutide injection 1.8 mg, placebo, or glimepiride 4 mg (one-half of the maximal approved dose in the United States), all as add-on to metformin
Make it easier to stick to healthier eating habits
(NEJM, 2023) reported that gastrointestinal adverse events were the dominant tolerability signal across all retatrutide arms and scaled steeply with the size of each escalation step [2][5]