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These may include Allergic reactions such as rash, hives, or difficulty breathing

Symptoms of gallbladder disease (severe right upper quadrant pain, fever, jaundice) also warrant prompt medical attention

Where possible, future studies should endeavor to rule out off-target metabolic effects, either by confirming minimal changes in the synthesis of metabolic off-targets or demonstrating that linked nitrogen metabolism pathways are not required for observed effects

This divide is largely driven by cost