In addition, this enzyme possesses an N-terminal domain which cleaves Gro3P into glycerol and inorganic phosphate (Pi) (in humans and other organisms, this reaction is catalyzed by a separate glycerol-3-phosphate phosphatase, a reaction also known as glycerol shunt)
However, serious side effects frequently arise following prolonged administration of levodopa, including dyskinesia, and there are currently no treatments available that affect disease progression
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* Estimated results based on available studies