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reported that after 18 months of CR, the trabecular bone score at the hip decreased by 0.22%, while cortical thickness declined by 2.45%

So they make that clarification there, right

This is the core group

It is also important to highlight a growing patient safety concern: retatrutide like other novel weight-loss agents has begun to appear through unregulated online sources and grey-market suppliers

Similar concerns have been seen with lipid outcomes with an increase in total cholesterol after cessation of semaglutide to near pretreatment levels and loss of around two-thirds of the benefit in triglycerides, while positive changes in LDL-C and HDL-C were more modest but appeared more durable (Table 2) [73]

Theres a spectrum, says Aaron Keshen, a psychiatrist at Dalhousie University and Nova Scotia Health in Canada