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Current evidence does not show semaglutide causes birth defects, but manufacturers recommend stopping the medication at least two months before attempting conception since it wasn't extensively studied in pregnancy

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However, oral administration is gaining traction, led by Rybelsus, the first oral GLP-1 approved by the FDA

The roadblock

[CrossRef] [Google Scholar] Global burden of 369 diseases and injuries in 204 countries and territories: A systematic analysis for the global burden of disease study 2019