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Approach to Persistent Pain After Surgery: My approach starts at the initial consultation, where I take a detailed history and physical examination, perform the in-office ultrasound, and provide the patient with a comprehensive assessment of all of their pain generators (not just endometriosis)

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SCFAs inhibit HDACs, increase acetylation of p70S6 kinase and phosphorylation of rS6, and augment the proportions of Th1, Th17, and IL-10-producing T cells, thus influencing the mTOR pathway (108)

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But the cagrilintide doesnt seem to have that same pronounced effect to activate these neurons that are responsible for GI symptomatology