Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT
Novo Nordisk, the Danish pharma company behind several GLP-1RA drugs (including Ozempic/Wegovy and Saxenda) grew its sales by over 30% in 2023, and its share price rose by over 70% in the last year, making it the most valuable European company by market capitalization
That slowing can be helpful for weight loss, but it may also affect the absorption of oral medications, including thyroid medication, in some patients
The improvement may reflect easing drug shortages, expanded insurance coverage and better management of side effects
By contrast, physiological levels of GLP-1 in the portal vein signal through vagal afferents and neurons in the nucleus tractus solitarius (NTS) (3)
Compounded GLP-1/GIP: Compounded tirzepatide , administered as one weekly self-administered injection