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Headache common in the early weeks, often improves as your body adjusts Constipation worth anticipating

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Pharmacologic Management of Orthostatic Hypotension Midodrine, a short-acting alpha-1 adrenergic agonist that acts via vasoconstriction, has been shown to alleviate symptoms of orthostatic hypotension and elevate blood pressure in multiple randomized placebo-controlled trials

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Certain pain medicationsparticularly opioidscan increase pain sensitivity over time through a process known as opioid-induced hyperalgesia

Riccardo De Giorgi, the studys lead author, emphasized that while these findings are promising, they need to be confirmed through further research, ideally in randomized controlled trials