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We recently reported the development of a Gs protein proximity assay that provides a direct, AMYR-selective, measurement of Gs protein recruitment and activation 22

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In contrast, autophagy induction is also shown to mediate CP chemosensitivity in several other reports

The standard 12-week escalation from 0.6mg to 2.4mg weekly balances efficacy with tolerability, producing 10-12% weight loss for most users