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[1] The Weight Loss Medication Revolution A decade ago, the pharmacologic options for obesity were few and underwhelming

If retatrutide receives marketing authorisation in the future, it would likely be subject to additional monitoring indicated by a black triangle () symbol which encourages enhanced Yellow Card reporting for new medicines to help identify any rare or delayed effects not captured in pre-approval trials

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Wilding et al., 2021

MK-677 doesnt affect those hormones but does impair insulin sensitivity