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Gastroenterology 141: 950958, 2011

Adjusted mean weight loss was highest in the tirzepatide group (19.52 0.70 kg), followed by semaglutide (16.63 0.73 kg) and liraglutide (13.18 0.74 kg)

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Originally developed from melanotan II during tanning peptide research in the 1990s, this cyclic heptapeptide unexpectedly demonstrated potent effects on sexual arousal and desire in preclinical studies