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It has documented effects on gut microbiome composition and may support gut health through prebiotic fermentation

Okamoto K, Aoki K

Cagrilintide has a plasma half-life of approximately 159 hours (~7 days) thanks to the acylated C20 fatty acid binding to albumin, which enables once-weekly dosing

Regarding the rest of the biomarkers, univariate ANCOVA with BMI adjustment was used with variables fitting a normal distribution and the Mann Whitney U test for those not fitting the normal distribution

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This depletion compromises the brains antioxidant defense, leading to increased oxidative damage and neuronal death