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In particular, they have used complementary models of CFTR silencing and blockade (by the CFTR inhibitor, CFTRinh-172) in freshly isolated human umbilical vein endothelial cells (HUVECs)

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Its results emphasize that while GLP-1 RAs are effective for weight management in obese populations, they are not substitutes for the vascular benefits associated with regular exercise in this specific clinical context

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