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Tesamorelin + Ipamorelin blends combine a GHRH analog (Tesamorelin) with a ghrelin mimetic (Ipamorelin) to stimulate pulsatile growth hormone release from the anterior pituitary, which then drives hepatic and tissue-level IGF-1 synthesis

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Brain cell metabolism was preserved in one trial, and the other found reduced amyloid-beta in extracellular vesicles, but neither trial found that GLP-1 drugs reduced the build-up of amyloid-beta in the brain or helped stave off cognitive decline

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