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However, VacA disrupts the integrity of the gastric epithelial barrier by forming channels or pores in the cell membrane, leading to increased permeability, and plays a role in regulating host cell apoptosis according to cell type and environmental conditions (Reyes, 2023
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doi: 10.1097/YCO.0b013e3283387b50 3
This stability has made the peptide a useful research tool in experimental models investigating peptide signaling under physiologically relevant biochemical conditions
Expression of two different monocarboxylate transporters in astroglial cells and neurons