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This is a significant development because OSA is extraordinarily common, underdiagnosed, and carries real cardiovascular risk through mechanisms including intermittent hypoxia, sympathetic nervous system activation, and systemic inflammation

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The enzyme encoded by the HSD17B10 gene is also known as 3-hydroxy-2-methylbutyryl-CoA dehydrogenase and as short chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) and as 3-hydroxyacyl-CoA dehydrogenase type II

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References : Vilsboll T, Krarup T, Sonne J, et al