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Enzyme pepsin, in the presence of hydrochloric acid acts on proteins and changes them into peptones and lower peptide fragments

Therefore, targeting the Gln metabolic network represents a unique opportunity to overcome therapeutic resistance and sensitize tumor cells to anticancer treatments, potentially offering greater benefit than AR-targeted monotherapy (39, 168)

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Basal cell density of tissue whole mounts was also quantified and the esophageal epithelium area was measured