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KRSR (lysine-arginine-serine-arginine) is a heparin-binding site found in fibronectin, vitronectin, bone sialoprotein, thrombospondin, and osteopontin [173]

Avoid reconstitution in buffers containing strong chelators (EDTA, EGTA) or reducing agents (DTT, -mercaptoethanol, TCEP), which can strip the copper from the tripeptide and convert the complex to free GHK

Am J Pathol (2011) 179(6):292030

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