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Instruments 1 H and 13 C NMR spectra were measured on a Bruker ARX 400 NMR spectrometer using CDCl 3 , DMSO- d 6 , or D 2 O as solvent and tetramethylsilane (TMS) as internal reference

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Of these parameters, PAI-1 and BNP levels were significantly decreased following a 14-week treatment with liraglutide (29% for PAI-1 with 1.25 mg liraglutide and 38% for hs-CRP with 1.90 mg liraglutide) versus placebo [40]

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