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The Journal of Clinical Endocrinology and Metabolism, 96 (1), 150-158

But those studies used oral supplements at specific doses, not transdermal patches

sequential administration such as administration of an oral form of a PDE-5 inhibitor, followed by administration of an intranasal form of a melanocortin agonist, preferably wherein the administration of the intranasal form of a melanocortin agonist is a determined time interval subsequent to oral administration of a PDE-5 inhibitor, optimal therapeutic results may be obtained with minimal adverse side effects

Try to stay out of the sun for about two weeks

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