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That includes people with abdominal weight gain, prediabetes or type 2 diabetes, elevated fasting insulin, high triglycerides, low HDL, nonalcoholic fatty liver disease, PCOS, or an elevated inflammatory marker in the setting of obesity

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GLP-1 also plays a role to reduce slow gastric emptying

zero published human clinical trials as of this writing a 2021 peer-reviewed review states plainly that no NNMT-targeted clinical trials have been reported

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Nature 548 , E13E14 (2017)