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Mechanistically, p53 decreases the monoubiquitination rate of histone H2B on lysine 120 (H2Bub1) in the SLC7A11 gene regulatory region by facilitating the nuclear translocation of the deubiquitinase USP7, leading to the inactivation of SLC7A11 expression in erastin-treated cells [122]

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[9] For wound healing specifically, the evidence is stronger than for cosmetic anti-aging, because wound models involve measurable endpoints (wound closure rate, tissue tensile strength, histological analysis) in controlled animal studies

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chinensis plant were extracted by using supercritical fluid extraction technology with CO 2 as the supercritical solvent and ethanol as the co-solvent (79)